SCIENCES BIOPHARMACEUTIQUES
SCIENCES BIOPHARMACEUTIQUES
| BPS3101 |
Genomics |
(3,0,0) 3 cr. |
| Broad introduction to genomics research, with strong emphasis on comparative genomics. Structure and organization of prokaryotic and eukaryotic genomes; gene mapping and DNA sequencing technologies; systematic methods for identification of gene function; drug discovery; proteomics. Introduction to bioinformatics and human genomic project. |
| Prerequisite: BIO2133. |
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| BPS3501 |
La g�nomique |
(3,0,0) 3 cr. |
| Introduction g�n�rale � la recherche en g�nomique mettant l'accent sur la g�nomique comparative. Structure et organisation du g�nome des procaryotes et eucaryotes; cartographie des g�nes et technologie de s�quen�age d'ADN, m�thodes syst�matiques utilis�es pour l'identification de la fonction des g�nes, d�couverte de drogues, prot�omique. Introduction � la bioinformatique et au projet du g�nome humain. |
| Pr�alable : BIO2533. |
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| BPS3901 |
Raport de stage CO-OP I / Co-op work term report I |
3 cr. |
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| BPS3902 |
Raport de stage CO-OP II / Co-op work term report II |
3 cr. |
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| BPS4006 |
Projet de recherche / Honours Project |
(0,0,9) 9 cr. |
| Cours visant � pr�parer l'�tudiant � des �tudes sup�rieures dans les domaines reli�s � la g�nomique. L'�tudiant se verra attribuer un projet de recherche avec un professeur d�sign� et soumettra un m�moire d�crivant les r�sultats de ses travaux. Concomitant: BPS 4000. Pour les �tudiants dans leur derni�re ann�e du B.Sc. avec sp�cialisation en Sciences biopharmaceutiques. |
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| BPS4019 |
Projet de recherche / Honours Project |
6 cr. |
| Cours visant � pr�parer l'�tudiant � des �tudes sup�rieures dans les domaines reli�s � la chimie m�dicinale. L'�tudiant se verra attribuer un projet de recherche avec un professeur d�sign� et soumettra un m�moire d�crivant les r�sultats de ses travaux. Pour les �tudiants dans leur derni�re ann�e du B.Sc. avec sp�cialisation en sciences biopharmaceutiques programme coop. This course is designed to prepare a student for graduate studies in the fields related to Medicinal Chemistry. The student is assigned a research project with a designated professor and submits a thesis describing the results of the research project For students in their last year of the biopharmaceutical science honours coop program only. |
| (ant�rieurement BPS4917) (formerly BPS4917). |
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| BPS4101 |
Human Genome Structure and Function |
(3,0,0) 3 cr. |
| First half of course will focus on human chromosomes, chromatin structure, genome organization, genetic and physical mapping and the human genome project. Second half will examine the genome at the level of the gene, and covers gene structure, gene regulation, gene splicing, mRNA transport and protein synthesis. Examples of inherited and acquired genetic diseases will be discussed. |
| Prerequisite: BCH3170 or BIO3170. |
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| BPS4102 |
Pharmaceuticals: Federal and International Regulations |
(3,0,0) 3 cr. |
| Introduction to Canadian Acts, Regulations and Guidelines pertaining to registration of agents affecting humans, animals and/or the environment. Comparative information on international trends and regulations. Basic knowledge for preparing submission packages in support of registration of new biopharmaceutical products. Discussion on the submission review process undertaken by Canadian regulatory agencies in carrying out detailed risk assessment of new products. Not necessarily offered every year. |
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| BPS4104 |
Bioinformatics Laboratory |
(1,0,4) 3 cr. |
| Principles of organization, retrieval, manipulation, and analysis of molecular data in genomics, proteomics and transcriptomics. Hands-on analysis of these data to solve biological questions using quantitative and computational methods. |
| Prerequisite: BPS 3101 and BIO 3102. |
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| BPS4111 |
Directed Studies in Biopharmaceutical Sciences |
3 cr. |
| This course involves a major literature review of a topic of current interest in the field. Upon completion of the written review the students will present and defend the key findings in a seminar. Students will choose their review subject in consultation with a prfessor assigned by the Program Director. For students in the last year of the Biopharmaceutical Science Honours program. |
| Cannot be combined for credit with BPS4006 or BPS4019. |
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| BPS4121 |
Biosynthesis and Natural Product Derived Medicines |
(3,0,0) 3 cr. |
| A study of the major biosynthetic pathways used by plants, bacteria and animals to synthesize the major families of secondary metabolites including fatty acids, phenolics, lignans, terpenes, steroids and alkaloids. The traditional use of certain natural products themselves as medicines and their value as lead compound for new drugs will be discussed. The synthesis of the natural products themselves or that of useful derivatives will also be studied. |
| Prerequisite: CHM3120. Cannot be combined for credit with BPS4123. |
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| BPS4123 |
Phytomedicines and Natural Product Drugs |
(3,0,0) 3 cr. |
| Ethnopharmacology and the discovery and development of natural product drugs. Phytochemistry and mode of action of major phytomedicines. Challenges in quality control and regulation. Pharmaceuticals derived from natural products. |
| Prerequisites: CHM2120, BIO2137. |
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| BPS4125 |
Medicinal Chemistry |
(3,0,0) 3 cr. |
| Drug design, discovery and synthesis, including structure-activity relationships, modes of action and recent therapeutic progress. Cannot be combined for credit with CHM 4123. |
| Prerequisite: CHM3120 or permission of the instructor. |
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| BPS4126 |
Synthetic and Medicinal Chemistry Laboratory |
(0,0,6) 3 cr. |
| The laboratory program will expose students to current methods and techniques used in the synthesis of pharmaceutical synthesis of pharmaceuticals and specialty chemicals. These include combinatorial chemistry, transition metal coupling reactions, enzyme mediated resolutions and complex carbohydrate synthesis. Products will be analyzed by modern spectroscopic methods for chemical purity and some will be tested in several biological screens. |
| Prerequisite: CHM3126. |
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| BPS4127 |
Advanced Techniques in Biosciences |
(0,0,6) 3 cr. |
| This laboratory course will expose students to advanced methods and techniques in biochemistry, molecular biology and cell biology. The course aims to allow a student to conduct a project involving the isolation, cloning, and expression of a gene. Gene function will be tested using biochemical and cellular assay systems. |
| Prerequisite: BCH3356 or BIO3151. Priority given to students in the 4th year of the Biochemistry, Biology or Biopharmaceutical Science programs who are not completing an honours research project. |
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| BPS4129 |
Advanced Chemical Biology |
(3,0,0) 3 cr. |
| This course focuses on chemical approaches to solving problems in molecular and cellular biology. Emphasis will be placed on multidisciplinary approaches to understand biological pathways and biological systems. Recent advances in chemical tool development for systems biology will be highlighted. Approaches to target selection for chemical intervention will also be covered. Topics include: chemical approaches to genomics and proteomics; protein design and engineering; chemistry in cellular imaging; chemistry in biotechnology; chemical genetics; rational and combinatorial approaches to pathway intervention; metabolic engineering. |
| Prerequisites: CHM2131 or CHM2132, BCH2140. Corequisites: CHM3120, BCH3170 or BIO3170. |
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| BPS4504 |
Laboratoire de bioinformatique. |
(1,0,4) 3 cr. |
| Principes d'organisation, de r�cup�ration, de manipulation et d'analyse de donn�es mol�culaires en g�nomique, prot�omique et transcriptomique. Analyses pratiques de ces donn�es pour r�soudre des questions biologiques en utilisant des m�thodes quantitatives et computationnelles. |
| Pr�alables: BPS3501 et BIO3502. |
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| BPS4511 |
�tudes dirig�es en sciences biopharmaceutiques |
3 cr. |
| Revue de la litt�rature sur un sujet d'actualit� dans le domaine. Les r�sultats de l'�tude sont pr�sent�s lors d'un s�minaire. Les �tudiants choisissent le sujet de l'�tude en consultation avec un professeur assign� par le directeur du programme. Pour les �tudiants d ans leur derni�re ann�e du B.Sc. sp�cialis� en sciences biopharmaceutiques. |
| BPS4511 ne peut pas �tre combin� avec BPS4006 ou BPS4019. |
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| BPS4521 |
Biosynth�se de m�dicaments d�riv�s de plantes m�dicinales |
(3,0,0) 3 cr. |
| L �tude des voies biosynth�tiques utilis�es par les plantes, les bact�ries et les animaux pour la synth�se d importantes familles de m�tabolites secondaires, incluant les acides gras, les ph�nols, lignanes, terp�nes, st�ro�des et alkalo�des. L usage traditionel de certains produits naturels comme m�dicaments et leurs valeurs comme substances de d�part pour la synth�se de nouveaux m�dicaments seront �tudi�s. La synth�se de produits naturels ou de leurs d�riv�s sera aussi �tudi�e. |
| Pr�alable: CHM3520. BPS4521 et BPS4523 sont mutuellement exclusifs. |
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| BPS4523 |
Produits naturels et phytom�dicaments |
(3,0,0) 3 cr. |
| Ethnopharmacologie; d�couverte et d�veloppements de m�dicaments provenant de produits naturels. Phytochimie et mode d'action des principaux phytom�dicaments. D�fis dans le contr�le de qualit� et la r�glementation. Produits pharmaceutiques d�riv�s de compos�s naturels. |
| Pr�alables : CHM2520, BIO2537. |
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| BPS4525 |
Chimie m�dicinale |
(3,0,0) 3 cr. |
| Conception, d�couverte et synth�se des m�dicaments incluant la relation entre la structure et l'activit�, les modes d'action ainsi que les progr�s r�cents en recherche th�rapeutique. Les cours CHM4523 et BPS 4525 sont mutuellement exclusifs. |
| Pr�alable : CHM3520 ou permission du professeur. |
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| BPS4526 |
Laboratoire de chimie m�dicinale et synth�se organique |
(0,0,6) 3 cr. |
| Le programme du laboratoire exposera les �tudiants aux diff�rentes m�thodes et techniques utilis�es en synth�se organique. Ceci inclut la chimie combinatoire, la synth�se des hydrates de carbone complexes, r�solution enzymatique et r�action de couplage utilisant les m�taux de transition. Les produits seront caract�ris�s par spectroscopie moderne. (RMN, IR, etc.) et quelques-uns seront soumis � plusieurs tests biologiques. |
| Pr�alable : CHM3526. |
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| BPS4527 |
Techniques avanc�es en biosciences |
(0,0,6) 3 cr. |
| Les �tudiants participant � ce cours seront expos�s � des m�thodes et des techniques avanc�es en biochimie, en biologie mol�culaire et en biologie cellulaire. L'emphase sera mise sur le design exp�rimental et sur l'usage appropri� de cont�les. Le but du cours est de permettre � l'�tudiant de mener � bien un projet impliquant l'isolation, le clonage et l'expression d'un g�ne. La fonction du g�ne sera �tudi�e en utilisant des syst�mes d'essais biochimiques et cellulaires. |
| Pr�alable : BCH 3756 ou BIO3551. Priorit� accord�e aux �tudiants et �tudiantes de 4i�me ann�e des programmes de biochimie, biologie ou sciences biopharmaceutiques qui ne sont pas inscrits au projet de recherche |
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| BPS4900 |
S�minaire / Seminar |
(0,0,10) 3 cr. |
| Expos�s par les �tudiants et discussions ax�s sur diff�rents aspects des sciences biopharmaceutiques. Pour les �tudiants dans leur derni�re ann�e du B.Sc. avec sp�cialisation en Sciences biopharmaceutiques. Presentations by students on recent trends in various aspects of biopharmaceutical sciences will be discussed. For students in their last year of the Biopharmaceutical Science Honours program only. |
| (ant�rieurement BPS4000) (formerly BPS4000). |
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| BPS4901 |
Rapport de stage CO-OP III Co-op work term report III |
3 cr. |
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| BPS4902 |
Rapport de stage Co-op IV Co-op work term report IV |
3 cr. |
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