Riadh Hammami

Le Dr Hammami a complété en 2004 sa maîtrise en biochimie à l'Institut Pasteur de Tunis, Université de Tunis El Manar. Il a obtenu en 2009 son Doctorat en Biologie Moléculaire et Cellulaire de l'Université de Lille1 - Sciences & Technologies (France) en cotutelle avec l'Université de Tunis El Manar (Tunisie). Il a ensuite complété cinq ans de formation postdoctorale en sciences et technologies des aliments à l'Université Laval, Canada. Il a été ensuite professionnel de recherche à l'Institut sur la Nutrition et les Aliments Fonctionnels (INAF), Université Laval. En 2017, le Dr Hammami a rejoint l'École des Sciences de la Nutrition, Faculté des sciences de la santé, à l'Université d'Ottawa en tant que professeur adjoint en microbiologie intestinale.

Le domaine d’expertise du Dr. Hammami se situe dans l’étude des bactériocines, des probiotiques et de leur potentiel d’utilisation pour moduler l’équilibre du microbiote intestinal humain et animal, et en industrie alimentaire. Il a également une solide expertise dans le développement de bases de données et outils bioinformatiques, ainsi que leur application pour le développement de nouveaux peptides antimicrobiens.

• Gut Microbiology Lab

• Vimont A., Fernandez B., Hammami R., Ababsa A., Daba H., and Fliss I. (2017) Bacteriocin-producing Enterococcus faecium LCW 44: a high potential probiotic candidate from raw camel milk. Frontiers in Microbiology, doi:10.3389/fmicb.2017.00865.
• Liato V., Hammami R., and Aïder M. (2017) Influence of electro-activated solutions of weak organic acid salts on microbial quality and overall appearance of blueberries during storage., Food Microbiology 64:56–64.
• Hanchi H., Hammami R., Gingras H., Kourda R., Bergeron M., Ben Hamida J., Ouellette M. and Fliss I. (2017) Inhibition of methicillin-resistant Staphylococcus aureus and of Clostridium difficile by durancin 61A: synergy with bacteriocins and antibiotics. Future Microbiology 12(3):205-212.
• Persico M., Mikhaylin S., Doyen A., Firdaous L., Hammami R., Bazinet L. (2016) How peptide physicochemical and structural characteristics affect anion-exchange membranes fouling by a tryptic whey protein hydrolysates. Journal of Membrane Science 520: 914–923.
• Hanchi H., Hammami R., Fernandez B., Kourda R., Ben Hamida J. and Fliss, I. (2016) Simultaneous production of formylated and non-formylated enterocins L50A and L50B, and 61A, a new glycosylated durancin, by Enterococcus durans 61A, a strain isolated from artisanal fermented milk in Tunisia. Journal of Agricultural and Food Chemistry 64(18):3584-90.
• Ennaas N., Hammami R., Gomaa A., Bédard F., Biron E., Subirade M., Beaulieu L. and Fliss I. (2016) Collagencin, an antibacterial peptide from fish collagen: activity, structure and interaction dynamics with membrane. Biochemical and Biophysical Research Communications 473(2):642-7.
• El Arbi M., Jalléli K., Trigui F., Pigeon P., Görmen M., Top S. , Aifa S., Fliss I., Jaouen G., and Hammami R. (2016). Efficacy of a novel ferrocenyl diaryl butene citrate compound as a biocide for preventing healthcare-associated infections. Medicinal Chemical Communications 7:948-954.
• Le Lay C., Fernandez B., Hammami R., Ouellette M. and Fliss I. (2015) On Lactococcus lactis UL719 competitivity and nisin (Nisaplin®) capacity to inhibit Clostridium difficile in a model of human colon. Frontiers in Microbiology 6:1020.
• Samandoulgou I., Hammami R., Morales Rayas R., Fliss I. and Jean J. (2015) Stability of Secondary and Tertiary Structures of Virus-Like Particles Representing Noroviruses: Effects of pH, Ionic Strength, and Temperature and Implications for Adhesion to Surfaces. Applied and Environmental Microbiology 81(22):7680-6.
• Hammami R., Ben Abdallah N. and Fliss I. (2015). Symbiotic maple saps minimize disruption of the mice intestinal microbiota after oral antibiotic administration. International Journal of Food Sciences and Nutrition 66(6):665-71.
• Ennaas N., Hammami R., Beaulieu L. and Fliss I. (2015) Production of antibacterial fraction from Atlantic mackerel (Scomber scombrus) and its coproducts using commercial enzymes. Food and Bioproducts Processing 96: 145–153.
• Ennaas N., Hammami R., Beaulieu L. and Fliss I. (2015) Purification and characterization of antibacterial peptides from protamex hydrolysate of Atlantic mackerel (Scomber scombrus) coproducts. Biochemical and Biophysical Research Communications 462(3).
• Hammami R., Bédard F., Gomaa A., Subirade M., Biron E. and Fliss I. (2015) Lasso-inspired peptides with distinct antibacterial mechanisms. Amino acids 47(2).
• Théolier J., Fliss I., Jean J. and Hammami R. (2014) Antimicrobial peptides of dairy proteins: from fundamental to applications, Food Reviews International 30:134-154.
• Théolier J., Hammami R., Fliss I. and Jean J. (2014) Antibacterial and antifungal activity of water soluble extracts from Mozzarella, Gouda, Swiss and Cheddar commercial cheeses produced in Canada, Dairy science and technology 94(5):427-438.
• El Arbi M., Théolier J., Pigeon P., Jallali K., Top S., Aifa S., Fliss I., Jaouen G. and Hammami R. (2014) Antibacterial properties and mode of action of new triaryl butenes citrates compounds. European Journal of Medicinal Chemistry 76:408-413.
• Hanchi H., Hammami R., Ben Hamida J., Kourda R. and Fliss I. (2014) Bacteriocinogenic properties and probiotic potential of enterococci, Archives of Microbiology 196(5):331-44.
• Fernandez B., Hammami R., Savard P., Jean J. and Fliss I. (2013) Pediococcus acidilactici UL5 and Lactococcus lactis ATCC 11454 are able to survive and produce their bacteriocins under simulated gastrointestinal conditions, Journal of Applied Microbiology 116:677-688.
• Théolier J., Jean J., Fliss I. and Hammami R. (2013) MilkAMP: a comprehensive database for antimicrobial peptides form dairy origin, Dairy science and technology 94(2):181-193.
• Théolier J., Hammami R., Labelle P., Fliss I. and Jean J. (2013) Purification and identification of antimicrobial peptides from whey protein hydrolysates, Journal of Functional Foods 5(2):706–714.
• Hammami R., Fernandez B., Lacroix C. and Fliss I. (2013) Anti-Infective properties of bacteriocins: an update, Cellular and Molecular Life Sciences 70(16):2947-2967.
• Le Blay G., Hammami R., Lacroix C., Fliss I. (2012) Stability and inhibition activity of pediocin PA-1 against Listeria in simulated physiological conditions of the human terminal ileum, Probiotics and Antimicrobial Proteins 4(4):250-258.
• Naghmouchi K., Hammami R., Fliss I., Teather R., Drider D., Baah J. (2012) Colistin A and colistin B among inhibitory substances of Paenibacillus polymyxa JB05-01-1, Archives of Microbiology 194(5):363-370.
• Yang Z., Yu Y., Yao L., Li G., Wang L., Hu Y., Zhang H., Xie X., Hammami R., Razavi R., Zhong Y., Liang X. (2011) DetoxiProt: an integrated database for detoxification proteins, BMC Genomics 12(Suppl 3):S2.
• Hammami R., Farhat I., Zouhir I. and Fedhila S. (2011) Detection and extraction of anti-listerial compounds from Calligonum comosum, a medicinal plant from arid regions of Tunisia, Afr J Tradit Complement Altern Med 8(3):322-327.
• Zouhir A., Hammami R., Ben Hamida J. and Fliss I. (2010) A new structure-based classification of Gram-positive bacteriocins, The Protein Journal 29(6): 432-9.
• Hammami R. and Fliss I. (2010) Current trends in the antimicrobial agents research: chemo- and bioinformatic approaches, Drug Discovery Today 15(13-14) 540-546.
• Hammami R., Zouhir A., Le Lay C., Ben Hamida J. and Fliss I. (2010) BACTIBASE second release: a database and tool platform for bacteriocins characterization, BMC Microbiology 10: 22.
• Hammami R., Ben Hamida J., Vergoten G., Lacroix J.M., Solomianny M.C., Neffati M., Fliss I (2009). A new antimicrobial peptide isolated from Oudneya africana seeds, Microbiol. Immunol. 53(12): 658-666.
• Hammami R., Ben Hamida J., Vergoten G., Fliss I. (2009) PhytAMP: a database dedicated to antimicrobial plant peptides, Nucleic Acids Research 37: D963-8.
• Hammami R., Zouhir A., Ben Hamida J., Neffati M., Vergoten G., Naghmouchi K., Fliss I. (2009) Antimicrobial properties of aqueous extracts from three medicinal plants growing wild in arid regions of Tunisia, Pharmaceutical Biology 47(5): 452-457.
• Hammami R., Zouhir A., Naghmouchi K., Ben Hamida J. and Fliss I. (2008) SciDBMaker: new software for computer-aided design of specialized biological databases, BMC Bioinformatics, 9: 121.
• Naghmouchi K., Drider D., Hammami R. and Fliss, I. (2008) Effect of antimicrobial peptides: divergicin M35 and nisin A on Listeria monocytogenes LSD530 potassium, Current Microbiology, 56(6): 609-12.
• Daghfous D., Chatti A., Hammami R., Landoulsi A. (2008) Modeling of the full-length Escherichia coli SeqA protein, in complex with DNA, Pathologie Biologie (Paris) 57(3):e61-e66.
• Hammami R., Zouhir A., Ben Hamida J. and Fliss I. (2007) BACTIBASE: a new web-accessible database for bacteriocin characterization, BMC Microbiology, 7: 89.

Chapitres de livres

• Fliss I., Hammami R. and Le Lay C. (2011) Biological control of human digestive microbiota using antimicrobial cultures and bacteriocins in Protective cultures, antimicrobial metabolites and bacteriophages for food and beverage biopreservation, Ed. C. Lacroix, Woodhead Publishing, Cambridge, UK. In press.
• Hammami R. and Fliss I.  (2011) Use of SciDBMaker as tool for the design of specialized biological databases in Visual Analytics and Interactive Technologies: Data, Text and Web Mining Applications, edited by Q. Zhang, R. Segall and M. Cao, IGI Global, pages 251-265 (DOI: 10.4018/978-1-60960-102-7.ch015).
• Hammami R., Zouhir A., Le Lay C., Ben Hamida J. and Fliss I. (2011) Database mining for bacteriocin discovery in Natural Antimicrobials in Food quality and Food Safety, Ed. M. Rai and M.L. Chikindas, CAB International, UK.