2019 Translational Research Grants set stage for exciting bench-to-bedside innovation

Faculty of Medicine
Faculty of Medicine
A diagram of the heart within the human body.
The Faculty of Medicine, The Ottawa Hospital and the University of Ottawa Heart Institute are pleased to announce the recipients of this year’s TRG grants.

The Faculty of Medicine, together with The Ottawa Hospital and the University of Ottawa Heart Institute, are pleased to announce the successful applicants of the Translational Research Grant (TRG) competition.

Translational research coordinates the application of novel discoveries in biological sciences to practical uses in pharmaceutical or clinical settings. The TRG program promotes such research and collaboration between basic scientists and clinical researchers throughout the Faculty, providing seed funding to test new, innovative ideas and facilitating future grant support.

Basic scientists and clinicians teamed up to submit joint applications as co-PIs on specific research projects. Each grant, up to $50K to be used over one to two years, is made up of matching funds from each partner: the basic science department or research institute, and the clinical department.

The program is managed and chaired by the vice-dean, research and the director of PhD research, Department of Medicine. Applications were evaluated by an expert committee, with priority given to those involving new investigators and new basic science/clinical collaborations.

Congratulations to the recipients of the eight grants awarded in the 2019 competition:

Team: Dr. Michele Ardolino and Dr. Carolyn Nessim
Faculty of Medicine Department(s)/Research Institute(s): Department of Biochemistry, Microbiology and Immunology / Department of Surgery
Title: Building a cell atlas of human sarcoma through single-cell-RNA-sequencing

Team: Dr. Dylan Burger, Dr. Manoj Lalu, and Dr. Darryl Davis
Faculty of Medicine Department(s)/Research Institute(s): Ottawa Hospital Research Institute / Department of Anesthesiology and Pain Medicine / University of Ottawa Heart Institute / Division of Cardiology
Title: Mesenchymal stromal cell derived exosomes as a preconditioning therapy for cardiac ischemia-reperfusion injury

Team: Dr. Thien-Fah Mah and Dr. Hesham Abdelbary
Faculty of Medicine Department(s)/Research Institute(s): Department of Biochemistry, Microbiology and Immunology / Division of Orthopaedic Surgery
Title: Use of a novel, clinically representative hip replacement rat model to assess pseudomonas aeruginosa biofilm-based periprosthetic joint infections

Team: Dr. Erin Mulvihill, Dr. Mary-Ann Doyle, and Dr. Erin Kelly
Faculty of Medicine Department(s)/Research Institute(s): University of Ottawa Heart Institute / Department of Medicine
Title: SGLT-2 inhibitors, GLP-1 agonists and hyperglucagonemia in non-alcoholic fatty liver disease and type 2 diabetes

Team: Dr. Mireille Ouimet and Dr. Juan Grau
Faculty of Medicine Department(s)/Research Institute(s): Department of Biochemistry, Microbiology and Immunology / Department of Surgery
Title: Analysis of human tissues to identify specific cellular resistance to atherosclerosis: A translational research approach

Team: Dr. Jennifer Reed and Dr. Girish Nair
Faculty of Medicine Department(s)/Research Institute(s): University of Ottawa Heart Institute / Division of Cardiology / Cardiac Electrophysiology Group
Title: Examining the role of high-intensity interval training on glycemic variability and symptomatology: A novel treatment approach for patients with atrial fibrillation and diabetes?

Team: Dr. Subash Sad and Dr. Catherine Ivory
Faculty of Medicine Department(s)/Research Institute(s): Department of Biochemistry, Microbiology and Immunology / Division of Rheumatology
Title: Evaluation of inflammatory cell death in the pathogenesis of systemic lupus erythematosus

Team: Dr. Jim Sun and Dr. Gonzalo Alvarez
Faculty of Medicine Department(s)/Research Institute(s): Department of Biochemistry, Microbiology and Immunology / Department of Medicine
Title: Decoding the epigenetic signature of tuberculosis using human lung cells

 

A diagram of the heart within the human body.