Faculty of Medicine Translational Research Grant competition sets stage for exciting bench-to-bedside innovation

Faculty of Medicine
Faculty of Medicine
A diagram of the heart within the human body.
This year’s cohort will apply biological sciences to advance heart, lung and placental function, prosthetic joint health and physician communication.

The Faculty of Medicine Research Office, together with The Ottawa Hospital and the University of Ottawa Heart Institute, is pleased to announce the successful applicants of the Translational Research Grant (TRG) competition.

Translational research coordinates the application of novel discoveries in biological sciences to practical uses in pharmaceutical or clinical settings. The TRG program promotes such research and collaboration between basic scientists and clinical researchers throughout the Faculty, providing seed funding to test new, innovative ideas and facilitating future grant support.

Basic scientists and clinicians teamed up to submit joint applications as co-PIs on specific research projects. Each grant, up to $50K to be used over one to two years, is made up of matching funds from each partner: the basic science department or research institute, and the clinical department.

The program is managed and chaired by the vice-dean, research and the director of PhD research, Department of Medicine. Applications were evaluated by an expert committee, with priority given to those involving new investigators and new basic science/clinical collaborations.

Congratulations to the recipients of the nine grants awarded in the 2018 competition:

Team: Dr. Robert deKemp (PhD) and Dr. Jakov Shlik (MD)
Faculty of Medicine Department(s)/Research Institute(s): University of Ottawa Heart Institute & Division of Cardiology/ Department of Psychiatry
Title: Imaging Myocardial Innervation in Post-Traumatic Stress Disorder

Team: Dr. Steven Hawken (PhD), Dr. Shannon Bainbridge (PhD), Dr. Dina El Demellawy (MD), and Dr. David Grynspan (MD)
Faculty of Medicine Department(s)/Research Institute(s): Ottawa Hospital Research Institute/Department of Obstetrics and Gynecology/Department of Pathology and Laboratory Medicine
Title: The missing link: Integrating placental pathology into existing pregnancy, birth and childhood health repositories

Team: Dr. Carolina Ilkow (PhD) and Dr. Hesham Abdelbary (MD)
Faculty of Medicine Department(s)/Research Institute(s): Department of Biochemistry, Microbiology and Immunology/Department of Surgery (Division of Orthopaedic Surgery)
Title: A tailored antimicrobial strategy for prosthetic joint infections caused by Staphylococcus aureus biofilm: combining the powers of bacteriophages and antibiotics

Team: Dr. Kyoung-Han Kim (PhD) and Dr. Peter Liu (MD)
Faculty of Medicine Department(s)/Research Institute(s): Department of Cellular and Molecular Medicine/University of Ottawa Heart Institute & Division of Cardiology
Title: Metabolic reprogramming in heart failure to ketone utilization—Unraveling the enigma of cardiac cachexia

Team: Dr. Kori LaDonna (PhD) and Dr. Glenn Posner (MD)
Faculty of Medicine Department(s)/Research Institute(s): Department of Innovation in Medical Education/Department of Obstetrics and Gynecology
Title: Assessing physician communication skills: validating the ‘secret shopper’ scorecard

Team: Dr. Wenbin Liang (PhD) and Dr. Darryl Davis (MD)
Faculty of Medicine Department(s)/Research Institute(s): Department of Cellular and Molecular Medicine/University of Ottawa Heart Institute & Division of Cardiology
Title: Cellular and Molecular Mechanisms Underlying Cardiac Sinus Node Dysfunction

Team: Dr. Lynn Megeney (PhD) and Dr. Lisa Mielniczuk (MD)
Faculty of Medicine Department(s)/Research Institute(s): Ottawa Hospital Research Institute/University of Ottawa Heart Institute & Division of Cardiology
Title: Evaluation of Right Ventricular Adaptation in the SU5416-Hypoxia Rat Model of Pulmonary Arterial Hypertension

Team: Dr. Benjamin Rotstein (PhD) and Dr. David Messika-Zeitoun (MD)
Faculty of Medicine Department(s)/Research Institute(s): Department of Biochemistry, Microbiology and Immunology/University of Ottawa Heart Institute & Division of Cardiology
Title: Imaging valvular matrix remodeling to predict progression of aortic stenosis

Team: Dr. Alain Stintzi (PhD) and Dr. Juthaporn Cowan (MD)
Faculty of Medicine Department(s)/Research Institute(s): Department of Biochemistry, Microbiology and Immunology/Department of Medicine
Title: The effect of immunoglobulin treatment on lung and gut microbiome in patients with Chronic Obstructive Pulmonary Disease

A diagram of the heart within the human body.