Faculty of Medicine’s 2020 Translational Research Grants set stage for exciting bench-to-bedside innovation

Faculty of Medicine
Faculty of Medicine
The TRG program promotes research and collaboration between basic scientists and clinical researchers, providing seed funding to test new, innovative ideas and facilitating future grant support.

The Faculty of Medicine, together with the University of Ottawa Heart Institute, Bruyère Research Institute, and Children’s Hospital of Eastern Ontario, are pleased to announce the successful applicants of the Translational Research Grant (TRG) competition.

Translational research coordinates the application of novel discoveries in biological sciences to practical uses in pharmaceutical or clinical settings. The TRG program promotes such research and collaboration between basic scientists and clinical researchers throughout the Faculty, providing seed funding to test new, innovative ideas and facilitating future grant support.

Basic scientists and clinicians teamed up to submit joint applications as co-PIs on specific research projects. Each grant, up to $50K to be used over one to two years, is made up of matching funds from each partner: the basic science department or research institute, and the clinical department.

The program is managed and chaired by the vice-dean, research and the director of PhD research, Department of Medicine. Applications were evaluated by an expert committee, with priority given to those involving new investigators and new basic science/clinical collaborations.

Congratulations to the recipients of the 7 grants awarded in the 2020 competition:

 

  • Dr. Michele Ardolino and Dr. Arleigh McCurdy

Faculty of Medicine Department(s)/Research Institute(s): Department of Biochemistry, Microbiology and Immunology / Department of Medicine

Title: Trogocytosis: A New Immune Escape Mechanism in Multiple Myeloma

 

  • Dr. Mark Campbell, Dr. Jeffrey Dilworth, and Dr. Sasha Carsen

Faculty of Medicine Department(s)/Research Institute(s): Bruyère Research Institute / Children’s Hospital of Eastern Ontario, Department of Surgery

Title: Determining the cartilage regeneration potential of novel stem cell populations to repair cartilage defects

 

  • Dr. Mireille Khacho and Dr. Jodi Warman-Chardon

Faculty of Medicine Department(s)/Research Institute(s): Department of Biochemistry, Microbiology and Immunology / Department of Medicine

Title: Unlocking Myotonic Dystrophy: Characterization of mitochondrial and muscle stem cell dysfunctions in DMI1 patients

 

  • Dr. Kyoung-Han Kim, Dr. Erin Mulvihill, and Dr. Louise Sun

Faculty of Medicine Department(s)/Research Institute(s): Department of Cellular and Molecular Medicine / Department of Biochemistry, Microbiology and Immunology / University of Ottawa Heart Institute

Title: Chasing heart failure patients susceptible to a wasting syndrome, cardiac cachexia

 

  • Dr. Wenbin Liang and Dr. Darryl Davis

Faculty of Medicine Department(s)/Research Institute(s): Department of Cellular and Molecular Medicine / University of Ottawa Heart Institute and the Division of Cardiology

Title: iPSC modelling of postoperative atrial fibrillation

 

  • Dr. Gergely Silasi and Dr. Richard Aviv

Faculty of Medicine Department(s)/Research Institute(s): Department of Cellular and Molecular Medicine / Department of Radiology

Title: Hemorrhagic transformation of microinfarcts

 

  • Dr. Alain Stintzi, Dr. Angela Crawley, and Dr. Angela Cheung

Faculty of Medicine Department(s)/Research Institute(s): Department of Biochemistry, Microbiology and Immunology / Department of Medicine

Title: Defining pathogenic mechanisms involved in primary sclerosing cholangitis through the multiomic evaluation of the gut microbiota and immunophenotypes of extreme phenotypes