| Fall | Winter |
|---|---|
| TMM30091 | TMM30092 |
| TMM3101 | TMM3103 |
| TMM3102 | 6 Credits of optional courses with 3000-level TMM or PHS course codes |
| TMM3104 | 3 Credits of courses in either humanities or social science |
For the list of optional 3000-level TMM or PHS courses, please consult the program catalogue.
This course facilitates the development of core technical, analytical and scientific communication skills required for successful future biomedical studies and careers. The course has two parts, an interactive training part that develops foundational knowledge of biomedical research approaches and hands-on expertise with commonly-used laboratory techniques, and a practical part that reinforces acquired competencies through the completion of two independent scientific projects under the supervision of a TMM Faculty member.
This course introduces the central contribution to inherited and chronic disorders of molecular mechanisms involved in gene expression, protein translation, DNA replication, repair and recombination. While the course emphasizes how these fundamental mechanisms are altered and assessed in human disease, it also introduces examples of unconventional disease mechanism that go beyond the central dogma of molecular biology.
By the end of this course, the student will be able to:
This course develops a foundation for elucidating the molecular basis of disease and molecular therapies by introducing knowledge and approaches to study the structure and the mechanisms of action of proteins and other biological macromolecules. The course emphasizes general principles determining the activity of biological macromolecules, methods to solve and visualize protein structures, and approaches used to understand how proteins, DNA, RNA, membranes and other biomolecules work in concert to support cells, tissues and organs.
By the end of this course, the student will be able to:
This course aims to provide a knowledge of the genetic and environmental factors that exert an influence on metabolic pathways, energy metabolism and human health. It covers a wide range of topics from dietary nutrients and bioenergetics to metabolic abnormalities and the prevention and treatment of metabolic diseases. The course emphasizes the development of an integrated perspective to understand how interconnectivity of genetic and environmental factors contribute to metabolic disease or exacerbate disease progression.
By the end of this course, the learners are expected to:
This course provides the knowledge foundation for understanding mechanisms by which aberrations in the cell machinery contribute to human disease. The course covers a broad range of mammalian cell biology topics from organelles and intracellular trafficking to apoptosis, differentiation and cell migration. The course also introduces the use of synthetic biology approaches to modulate cellular function or engineer entirely novel properties.
By the end of the course the learner should be able to:
This course offers an introduction to immunology with a focus on the cellular and molecular mechanisms of the immune system involved in the defense against infection and disease. It covers a range of topics from the cells and organs of the immune system to the molecular and clinical outcomes of immune responses, and emphasize the integration and application of this knowledge to understand how immunity and infection contributes to human diseases and their treatment.
By the end of this course, the student will be able to:
This course introduces fundamental topics of neurobiology and mechanisms of neurological disorders. The course covers a range of knowledge areas, from the anatomy of the nervous system and the cell types of the brain to mechanisms underlying developmental defects, cortical reorganization, neurogenesis and neurodegeneration, and emphasises how this knowledge is applied to neurological diseases such as epilepsy, autism and Alzheimer's.
By the end of this course, the student will be able to:
This course provides a comprehensive introduction to the foundations of systems biology and precision medicine with emphasis on practical applications of ‘-omics’ technologies in biomedical research and clinical decision-making. The course covers a range of topics ranging from medical genetics and the exploration of large datasets to identify disease genes and mechanisms, to integrated network perspectives of human diseases and synthetic biology approaches to engineer gene- and cell-based human therapeutics.
This course aims to enhance research and scientific communication skills through the application of computational biology tools to aid the analysis and interpretation of biomedical data and the production of publication-quality figures. The course provides a practical introduction to scientific computing with emphasizes on the creation of transparent and reusable code for robust data analysis in biomedical research and the creation of impressive visualizations and presentation graphics.
The course aims to provide knowledge of molecular mechanisms underlying heart failure, neuromuscular disease and cancer progression and the therapeutic applications of stem cell, RNA- and DNA-based therapies. The course emphasises reading of current scientific literature to define disease states and treatment avenues, and to explore the limitations and challenges faced by current translational efforts.
By the end of this course, the student will be able to:
Introduction to inquiry-based research Translational and molecular medicine (TMM) is a research-oriented undergraduate program that emphasizes current methodologies, techniques and technologies in biomedicine. This course will give students the opportunity to assess the current scientific literature and perform a real-world laboratory project. Participation in this course can serve as early entry point to the TMM program, a way to gain hands on-lab experience or a chance to explore biomedical research at the Faculty of Medicine. This course is open to first and second year students in any program in the Faculty of Science at the University of Ottawa or similar programs at other universities.
