Professor Chan holds the Canada Research Chair in Toxicology and Environmental Health. He studies the exposure of chemical contaminants found in the diet and the environment, particularly among Indigenous Peoples. Dr. Chan assesses the effects of these contaminants on ecosystem health and human health and develops new tools for risk assessment. In the laboratory, he uses different models, and biochemical techniques to better understand how chemicals affect the biological functions of wildlife and humans. His goal is to develop effective tools and programs for the management and promotion of environmental health for human populations.
Selected publications
- Sarma SN, Kimpe LE, Doyon VC, Blais JM, Chan HM. (2019). A metabolomics study on effects of polyaromatic compounds in oil sand extracts on the respiratory, hepatic and nervous systems using three human cell lines. Environ Res.178:108680. doi: 10.1016/j.envres.2019.108680.
- Ricketts P, Voutchkov M, Chan HM. (2019). Risk-Benefit Assessment for Total Mercury, Arsenic, Selenium, and Omega-3 Fatty Acids Exposure from Fish Consumption in Jamaica. Biol Trace Elem Res. doi: 10.1007/s12011-019-01965-3.
- Eccles KM, Pauli BD, Chan HM. (2019). The Use of Geographic Information Systems (GIS) for Spatial Ecological Risk Assessments: An example from the Athabasca Oil Sands area in Canada. Environ Toxicol Chem. doi: 10.1002/etc.4577.
- Hu XF, Stranges S, Chan HM. (2019) Circulating Selenium Concentration Is Inversely Associated With the Prevalence of Stroke: Results From the Canadian Health Measures Survey and the National Health and Nutrition Examination Survey. J Am Heart Assoc. 8(10):e012290. doi: 10.1161/JAHA.119.012290.
- Marushka L, Kenny TA, Batal M, Cheung WWL, Fediuk K, Golden CD, Salomon AK, Sadik T, Weatherdon LV, Chan HM. (2019). Potential impacts of climate-related decline of seafood harvest on nutritional status of coastal First Nations in British Columbia, Canada. PLoS One. 14(2):e0211473. doi: 10.1371/journal.pone.0211473.
- Kenny TA, XF Hu, HV Kuhnlein, SD Wesche, HM Chan. (2018). Dietary sources of energy and nutrients in the contemporary diet of Inuit adults: results from the 2007–08 Inuit Health Survey. Public health nutrition, 21(7):1319-1331.
- Ostertag SK, HM Chan (2018). Biomarkers of the cholinergic and dopaminergic signaling pathways in Arctic beluga whales (Delphinapterus leucas): relationship to methylmercury and selenium. Arctic Science, 1-16 dx.doi.org/10.1139/as-2017-0033.
- Juric AK, Batal M, David W, Sharp D, Schwartz H, Ing A, Fediuk K, Black A, Tikhonov C, Chan HM. (2018). Risk assessment of dietary lead exposure among First Nations people living on-reserve in Ontario, Canada using a total diet study and a probabilistic approach. J Hazard Mater.;344:55-63.
- Shao Y, Yamamoto M, Figeys D, Ning Z, Chan HM. (2016). Proteome profiling reveals regional protein alteration in cerebrum of common marmoset (Callithrix jacchus) exposed to methylmercury. Toxicology347-349:29-39.