Dr. Perry has four ongoing research projects that are unified by a common theme; the adaptation of fish to stressful or extreme environments.
- The role of stress hormones in controlling cardio respiratory function and blood gas transport in fish during environmental disturbances.
- The physiological and molecular nature of gill and renal transepithelial ion movements and their modulation during environmental and acid-base disturbances.
- The molecular basis of hypoxic pre-conditioning in zebra fish and the ontogenetic effects of chronic environmental disturbances on cardio respiratory function.
- The nature of oxygen and carbon dioxide sensing by chemoreceptors and its linkage to cardio respiratory control.
Selected publications
- Zimmer, A. M., Shir-Mohammadi, K., Kwong, R. W. M. and Perry, S. F. (2020). Reassessing the contribution of the Na+/H+ exchanger Nhe3b to Na+ uptake in zebrafish (Danio rerio) using CRISPR/Cas9 gene editing. J. Exp. Biol. 223, jeb215111.
- Yew, H. M., Zimmer, A. M. and Perry, S. F. (2020). Assessing intracellular pH regulation in H+-ATPase-rich ionocytes in zebrafish larvae using in vivo ratiometric imaging. The Journal of Experimental Biology 223, jeb212928.
- Mandic, M., Best, C. and Perry, S. F. (2020). Loss of hypoxia inducible factor 1a affects hypoxia tolerance in larval and adult zebrafish (Danio rerio). Proc. Roy. Soc. B 287, 20200798.
- Hughes, M. C., Zimmer, A. M. and Perry, S. F. (2019). Role of internal convection in respiratory gas transfer and aerobic metabolism in larval zebrafish (Danio rerio). American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 316, R255-R264.
- Gilmour, K. M. and Perry, S. F. (2018). Conflict and Compromise: Using Reversible Remodeling to Manage Competing Physiological Demands at the Fish Gill. Physiology 33, 412-422.