Dr. Lovell specializes in the design, construction, and utilization of fluorophores.
The Lovell Lab's research focuses on designing, constructing, and utilizing fluorophores for biological applications. Specifically, through i) constructing new fluorophores to report protein dynamics currently inaccessible with available probes, ii) designing new fluorescent scaffolds for single-molecule microscopy with superior photostability, and iii) establishing new single-molecule fluorescence microscopy methods.
Selected publications
- Lovell, T. C.*; Branchaud, B. P.; Jasti, R.* An Organic Chemist’s Guide to Understanding Common and New and Unusual Fluorophores. Eur. J. Org. Chem. 2024, 27, e202301196.
- Gidi, Y. A.‡; Ramos-Sanchez, J.‡; Lovell, T. C.; Glembockyte, V.; Cheah, I. K.; Schnermann, M. J.; Halliwell, B.; Cosa, G. Superior Photoprotection of Cyanine Dyes with Thio-imidazole Amino Acids. J. Am. Chem. Soc. 2023, 145, 19571–19577.
- Lovell, T. C.; Bolton, S. G.; Kenison, J. P.; Shangguan, J.; Otteson, C. E.; Civitci, F.; Nan, X.; Pluth, M. D.; Jasti, R. Biocompatible, subcellular targeted nanohoop for one- and two-photon live cell imaging. ACS Nano 2021, 15, 15285–15293.
- Lovell, T. C.; Garrison, Z. R.; Jasti, R. Synthesis, Characterization and Computational Investigation of Bright Orange-emitting Benzothiadiazole [10]Cycloparaphenylene. Angew. Chem. 2020, 59, 14363-14367.