Imagerie par ultrason

Ultrasound imaging modes: 

• B-Mode imaging (brightness) 
• M-Mode imaging (motion) 
• PW (Pulsed Wave) Doppler Mode imaging 
• Color Doppler Mode imaging 
• Power Doppler imaging 
• Contrast Mode imaging 

Available transducers 

• Red for mouse cardiac imaging with frame rates greater than 300 frames per second, 18-38 MHz (MS-400) 
• Yellow for rat cardiac and abdominal imaging, 13-24 MHz (MS-250) 
• Blue for mouse cancer and abdominal imaging, 22-55 MHz (MS-550D) 

Custom measurement packages: 

• Cardiac measurement package 
• Abdominal measurement package 
• Vascular measurement package 
• Embryology measurement package 
• Ophthalmology application package 

Application packages 

• Cardiology 
• General imaging

• Ultrasound is unique in its ability of real-time imaging (particularly useful in cardiology for assessing cardiac function and fluid dynamics) 
• Multiple modes available: B-mode, M-mode, Doppler (color, PW, tissue)  
• Imaging multiple time points and targets  
• Excellent spatial resolution (≤ 100 µm)  
• Contrast agents available (microbubbles) for tissue perfusion  
• Cost and time effective 

• Limited depth penetration (around 1-3 cm with frequencies 25-75 MHz, respectively)  
• Need for experienced user 

• Cardiac morphology and function, blood flow 
• Angiogenesis, inflammation 
• Functional and molecular vascular imaging of superficially localized tissues like skeletal muscle, subcutaneous tumors, and the brain 
• Kidney research: renal blood flow (ischemic-reperfusion-injury mouse model) 
• Liver imaging (hepatic blood flow, tumor size, non-alcoholic fatty liver disease) 
• Guided injections (joints, uterus) 
• Cancer research (sentinel lymph node) 
• Cranial (brain development, transcranial ultrasound) 

• Kanaan, G. N. et al. (2018); doi: http://dx.doi.org/10.1016/j.redox.2017.10.019 
• Deguise, M-O et al. (2020); doi: https://doi.org/10.1016/j.ebiom.2020.102750 
• Darwich, R. et al. (2017); doi: https://doi.org/10.1093/hmg/ddx009 
• Rehmani, T. et al. (2021) : doi : https://doi.org/10.3390/cardiogenetics11040018 
• Mlynarova, J. et al (2019) : doi : https://doi.org/10.1371/journal.pone.0214669