Submission Number: 456
Submission ID: 3241
Submission UUID: da961ee5-271d-4754-b23a-00cf3afb736b

Created: Sat, 11/04/2023 - 09:31
Completed: Sat, 11/04/2023 - 09:32
Changed: Sat, 11/04/2023 - 09:32

Remote IP address: 172.69.214.168
Submitted by: Anonymous
Language: English

Is draft: No
New student or staff member
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First name: Victor Jeffrey (Jeff)
Last name: Leyton
Email: [email protected]
Office or Lab Phone Number: 8195601323
Cell phone number: 8195601323
Home phone number: {Empty}
Status: Principal investigator
Your lab's department/institute: School of Pharmaceutical Sciences
Whose laboratory will you be working in?: Victor Jeffrey Leyton
Supervisor's email: [email protected]
With which species will you be working?: mice
If you will be working with aquatic species, please provide your date of birth for enrollment in the Experimental Fish Course online training: {Empty}
Have you received previous training on animal care and use in science?: Yes
Please indicate at which institution and the year this training was received:
I have approved animal protocols for the past 10 years at the Université de Sherbrooke where I was a principal investigator and I served on the Animal Ethics Committee for 2 years. 

Please provide a brief summary of this training and your experience working with animals:
I primarily work with immunodeficient mice (SCID and Nude) of both sexes. The models of human cancer entail i.p. implantation of human tumor cells or orthotopic implantation in the mammary fat pad. Therapeutic manipulations involve intravenous bolus injection of the experimental pharmaceuticals. The tumor implantation are performed with the mice under anaesthesia. The mice a awake for the intravenous injections. Tumor growth and mouse weight and overall appearance is measured every 3 days. Periodically, the sapehnous vein is nicked and 5-10 uL of blood is collected. The mice are awake for this procedure. Typically, the experiment goes until the tumor reaches the ethical limit volume. Mice are humanely euthanized.

Attach any relevant institutional certificates received: https://www.uottawa.ca/research-innovation/system/files/webform/acvs_registration_form/3241/2021-3121%20-%20Approbation%20finale%20-%20Victor%20Jeffrey%20Leyton.pdf
Topaz: I confirm
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