Optical imaging
The Preclinical Imaging Core (PCIC) facility houses equipment providing a range of applications for structural and functional imaging in live small rodents as well as ex vivo and in vitro studies.
IVIS spectrum
Our System
The PCIC houses the IVIS® Spectrum (Perkin Elmer). The IVIS Spectrum is equipped with filters enabling both bioluminescence and fluorescence 2D and 3D imaging. The equipment is operated through Living Image software which allows you to choose from 3 basic types of imaging: imaging of 1 target, spectral unmixing for imaging multiple targets, and 3D imaging. Using automatic settings allows for easy and comparable imaging that can be quantified both in 2D and 3D. Choice of different ROI types are available for in vivo, ex vivo, and in vitro imaging. The equipment gives the option of imaging up to 5 mice per image.
Examples of images acquired by our IVIS Spectrum
IR VIVO
PCIC is excited to welcome in the next few months a new member of the imaging equipment: optical imaging system IR VIVO by Photon etc. (Canada).
This special optical imaging equipment uses detection in the near infrared with emission spectral range 850-1620 nm. You can use the advantage of reduced light scattering, absorption, and auto-fluorescence as well as high spatial and temporal resolution and penetration depth. Addition of real-time imaging feature of this optical system is perfect for monitoring drug and metabolite kinetics. While imaging, you can also take advantage of contact-free monitoring of heartbeat and respiratory rate.
Discover this coming technology!
For more information visit IR VIVO™ | Photon etc.
